MARINE MICROALGAE Nannochloropsis OculataOCULATA ANTI VIRUSAS AN ALTERNATIVE VIRAL NERVOUS NECROTIC (VNN) ON HUMPACK GROUPER (Cromileptes altivelis)

Ach. Khumaidi

doi:10.5281/jsapi.v7i1.302

Ach. Khumaidi Program Studi Budidaya Perikanan, Akademi Perikanan Ibrahimy, Situbondo.

10.5281/jsapi.v7i1.302

Keywords: C. altivelis, ssRNA virus, VNN, N. oculata, antiviral.

Abstract

Viral nervous necrosis (VNN) is the causative agent of the disease that quite dangerous for the survival of grouper farming (C. altivelis). Impacts this virus attacks are capable of causing up to 100% mortality. For overcome attack VNN can be used materials of biological resources is N. oculata. Utilization marine microalgae N. oculata were able to improve the immune system, boost the immune response by improving the expression of Toll-like Receptor (TLR) expression Major Histocompitability Complex (MHC), were able to inducing antiviral genes (P56), and able to provide an anti-inflammatory effect. With these capabilities. Feasible to develop the utilization of marine microalgae N. oculata as an alternative to tackling VNN attack on C. altivelis.

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